Julia Bailey

Julia Bailey
Appointment Title: 
Adjunct Associate Professor
Type of Faculty: 
Part Time
310.206.6039
Areas of Interest: 

Genetic epidemiology of epilepsy and other neurological disorders, post traumatic stress disorder and schizophrenia. Focus on gene localization through family-based linkage and association methods as well as next generation deep sequencing technology.

Biographical Information: 

Dr. Bailey became interested in evolutionary biology and statistical genetics during her first degree working with insects. In graduate school she started studying Epidemiology and Human genetics. Most of her career has been focused on methods to find genes for complex traits using large extended pedigrees. These large, extended families allow the study of co-segregation of specific DNA and the clinical and subclinical phenotypes. Dr. Bailey studies families collected from various countries including Honduras, Mexico, Armenia and the United States, some families have over 100 members and more than 9 affected members.

 

Education: 
BSc, Honours, Evolutionary Biology, Concordia University, Montreal Quebec
PhD, Genetic Epidemiology, Yale University School of Public Health
This faculty member is available to serve as: 
MS Report Committee Member
Field Studies Advisor

Please check with the faculty member or their office about availability to serve during current academic period.

Selected Publications: 

Bailey JN, Patterson C, de Nijs L, Durón RM, Nguyen VH, Tanaka M, Medina MT, Jara-Prado A, Martínez-Juárez IE, Ochoa, Molina Y, Suzuki T, Alonso MA, Wight JE, Lin YC, Guilhoto L, Yacubian EMT, Machado-Salas J, Daga A, Yamakawa K, Grisar TM, Lakaye B, Delgado Escueta AV. EFHC1 variants in Juvenile Myoclonic Epilepsy: Reanalysis according to NHGRI and ACMG Guidelines for assigning disease causality. Genetics in Medicine, in press.

Wight JE, Lin Y, Nguyen V, Tanaka M, Bai D, Aftab S, Patterson C, Durón RM,  Medina MT, Bailey JN, Delgado-Escueta AV.  Identification of Juvenile Myoclonic Epilepsy Loci in Chromosomes 16p13.3, 13q31.1, and 4q35.2 in Honduran Families: Linkage to Epilepsy and Encephalography Trait. Mol Genet Genomic Med. 2016 Jan 23;4(2):197-210. doi: 10.1002/mgg3.195. eCollection 2016 Mar. PMID: 27066514

Bickeböller H, Bailey JN, Beyene J, Cantor RM, Cordell HJ, Culverhouse RC, Engelman CD, Fardo DW, Ghosh S, König IR, Lorenzo Bermejo J, Melton PE, Santorico SA, Satten GA, Sun L, Tintle NL, Ziegler A, MacCluer JW, Almasy L. Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees. BMC Proc. 2014 Jun 17;8(Suppl 1):S1. doi: 10.1186/1753-6561-8-S1-S1. eCollection 2014. PMID: 25519310

Goenjian AK, Noble EP, Steinberg AM, Walling DP, Stepanyan ST, Dandekar S, Bailey JN. Association of COMT and TPH-2 genes with DSM-5 based PTSD symptoms. J Affect Disord. 2014 Oct 22;172C:472-478. doi: 10.1016/j.jad.2014.10.034. PMID: 25451452

Chen H, Malzahn D, Balliu B, Li C, Bailey JN. Testing Genetic Association with Rare and Common Variants in Family Data. GenetEpidemiol. 2014 Sep;38 Suppl 1:S37-43. doi: 10.1002/gepi.21823. PMID: 25112186

Delgado-Escueta AV, Koeleman BP, Bailey JN, Medina MT, Durón RM. The quest for Juvenile Myoclonic Epilepsy genes. Epilepsy Behav. 2013 Jul;28 Suppl 1:S52-7. 

Tanaka M, Bailey JN, Bai D, Ishikawa-Brush Y, Delgado-Escueta AV, Olsen RW. Effects on promoter activity of common SNPs in 5' region of GABRB3 exon 1A. Epilepsia. 2012 Aug;53(8):1450-6.

Jara-Prado A, Martínez-Juárez IE, Ochoa A, González VM, Fernández-González-Aragón MD, López-Ruiz M, Medina MT, Bailey JN, Delgado-Escueta AV, Alonso ME (2012). Novel Myoclonin1/EFHC1 mutations in Mexican patients with juvenile myoclonic epilepsy. Seizure;21(7):550-4

Goenjian AK, Bailey JN, Walling DP, Steinberg AM, Schmidt D, Dandekar U, Noble EP (2012). Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms. J Affect Disord. 2012 Nov;140(3):244-52.

Kazma, R and Bailey, JN Population-based and Family-based Designs to Analyze Rare Variants in Complex Diseases. Genetic Epidemiology 35  1:S41-7.  

Bailey Julia N, Goenjian Armen K, Noble Ernest P, Walling David P, Ritchie Terry, Goenjian Haig A PTSD and dopaminergic genes, DRD2 and DAT, in multigenerational families exposed to the Spitak earthquake.. Psychiatry research. 2010; 178(3): 507-10.

Tanaka Miyabi, Olsen Richard W, Medina Marco T, Schwartz Emily, Alonso Maria Elisa, Duron Reyna M, Castro-Ortega Ramon, Martinez-Juarez Iris E, Pascual-Castroviejo Ignacio, Machado-Salas Jesus, Silva Rene, Bailey Julia N, Bai Dongsheng, Ochoa Adriana, Jara-Prado Aurelio, Pineda Gregorio, Macdonald Robert L, Delgado-Escueta Antonio V Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy.. American journal of human genetics. 2008; 82(6): 1249-61.

Goenjian Armen K, Bailey Julia N, Walling David P, Steinberg Alan M, Schmidt Devon, Dandekar Uma, Noble Ernest P Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms.. Journal of affective disorders. 2012; 140(3): 244-52.

Bai Dongsheng, Bailey Julia N, Durón Reyna M, Alonso María E, Medina Marco T, Martínez-Juárez Iris E, Suzuki Toshimitsu, Machado-Salas Jesús, Ramos-Ramírez Ricardo, Tanaka Miyabi, Ortega Ramón H Castro, López-Ruiz Minerva, Rasmussen Astrid, Ochoa Adriana, Jara-Prado Aurelio, Yamakawa Kazuhiro, Delgado-Escueta Antonio V DNA variants in coding region of EFHC1: SNPs do not associate with juvenile myoclonic epilepsy.. Epilepsia. 2009; 50(5): 1184-90.

Fairbanks Lynn A, Jorgensen Matthew J, Bailey Julia N, Breidenthal Sherry E, Grzywa Rachel, Laudenslager Mark L Heritability and genetic correlation of hair cortisol in vervet monkeys in low and higher stress environments.. Psychoneuroendocrinology. 2011; 36(8): 1201-8.

Goenjian Armen K, Noble Ernest P, Walling David P, Goenjian Haig A, Karayan Ida S, Ritchie Terry, Bailey Julia N Heritabilities of symptoms of posttraumatic stress disorder, anxiety, and depression in earthquake exposed Armenian families.. Psychiatric genetics. 2008; 18(6): 261-6.

Jara-Prado Aurelio, Martínez-Juárez Iris E, Ochoa Adriana, González Víctor M, Fernández-González-Aragón María Del Carmen, López-Ruiz Minerva, Medina Marco T, Bailey Julia N, Delgado-Escueta Antonio V, Alonso María Elisa Novel Myoclonin1/EFHC1 mutations in Mexican patients with juvenile myoclonic epilepsy.. Seizure : the journal of the British Epilepsy Association. 2012; 21(7): 550-4.

Medina M T, Suzuki T, Alonso M E, Durón R M, Martínez-Juárez I E, Bailey J N, Bai D, Inoue Y, Yoshimura I, Kaneko S, Montoya M C, Ochoa A, Prado A Jara, Tanaka M, Machado-Salas J, Fujimoto S, Ito M, Hamano S, Sugita K, Ueda Y, Osawa M, Oguni H, Rubio-Donnadieu F, Yamakawa K, Delgado-Escueta A V Novel mutations in Myoclonin1/EFHC1 in sporadic and familial juvenile myoclonic epilepsy.. Neurology. 2008; 70(22 Pt 2): 2137-44.

Fairbanks L A, Bailey J N, Breidenthal S E, Laudenslager M L, Kaplan J R, Jorgensen M J Environmental stress alters genetic regulation of novelty seeking in vervet monkeys.. Genes, brain, and behavior. 2011; 10(6): 683-8.

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